A Transmembrane Protein WAI-B2 Confers Multiple Disease Resistance in Wheat by Activating Autoimmunity.

ABSTRACT: Wheat (Triticum aestivum L.) is one of the world's most important food crops and its production is frequently threatened by diseases caused by several biotrophic pathogens, including stripe rust, leaf rust, stem rust and powdery mildew. Identifying and cloning genes that confer resistance to multiple-diseases hold significant value for breeding wheat cultivars with broad-spectrum disease resistance. In this study, a wheat autoimmunity-B2 (WAI-B2) gene is cloned from an ethyl methanesulfonate (EMS)-induced wheat autoimmunity mutant, 8P4087, and its role in resistance against multiple foliar diseases is characterized. WAI-B2 encodes a unique transmembrane protein that provides resistance to powdery mildew, stripe rust, leaf rust and stem rust in wheat. Further analysis reveals that WAI-B2 in

SUBMITTER: Li W 

PROVIDER: S-EPMC12806210 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature