ScMOVIR: a single-cell multi-omics database for human viral infections and immune responses.

ABSTRACT: Viral infections impose a substantial threat to human health, characterized by a wide range of pathogens, clinical manifestations, and complex immune responses. Single-cell multi-omics technologies have revolutionized the study of antiviral immunity by resolving cellular heterogeneity, transcriptional reprogramming, and clonal dynamics. However, no resource has yet comprehensively integrated such datasets in the context of viral infections. Here, we present scMOVIR, a single-cell multi-omics database for human viral infections and immune responses. The database systematically integrates transcriptomic, proteomic, and immune receptor repertoire profiles at single-cell resolution, compiling 8532 human samples across 114 viral species, subtypes, and strains. These datasets span 59 well-define

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12807708 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature