Human-scATAC-Corpus: a comprehensive database of scATAC-seq data.

ABSTRACT: Single-cell assay for transposase-accessible chromatin using sequencing (scATAC-seq) profiles chromatin accessibility at cellular resolution, making it possible to reveal epigenomic landscapes that govern gene regulation in a variety of cells. Nevertheless, heterogeneous feature spaces and complex processing pipelines have impeded the construction of an ensemble resource capable of supporting diverse downstream analytical scenarios. To address this gap, we present Human-scATAC-Corpus (https://health.tsinghua.edu.cn/human-scatac-corpus/), a comprehensive database of human scATAC-seq comprising 5 407 621 cells from 35 datasets across 37 tissues or cell lines. To support complementary use cases, each dataset is distributed in three aligned formats: cell-by-candidate cis-regulatory element mat

SUBMITTER: Chen X 

PROVIDER: S-EPMC12807747 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature