Gramene 2025: expanded comparative genomics and pathway resources, integrated search, and pan-genome portals for crop research.

ABSTRACT: Gramene (gramene.org) is a comprehensive reference database for comparative plant genomics and pathway analysis, integrating functional annotations, evidence-based curated pathways and their projections, and multi-omics datasets. Since our last report, Gramene has added crop-specific pan-genome portals for maize, sorghum, rice, and grapevine. These pan-genome portals host population-scale datasets and multiple assembled genomes per species, all anchored by shared reference genomes. Importantly, these portals now adopt standardized rsIDs for genetic variants, advancing FAIR data principles and enabling cross-database interoperability. The main site is now Gramene Plants, emphasizing its broad genome coverage. Release 69 features 233 reference genomes, curated pathways for 139 species, expre

SUBMITTER: Olson A 

PROVIDER: S-EPMC12807754 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature