Pulmonary and extra-pulmonary infections caused by classical and hypervirulent <i>Klebsiella pneumoniae</i>: a prospective cross-sectional study.

ABSTRACT:

Aim

Klebsiella pneumoniae (K. pneumoniae) is an opportunistic pathogen causing infections ranging from pulmonary disease to severe systemic illness. This study aimed to examine the relationships between infection site, pathotype, virulence, resistance, and clinical presentations to manage classical (cKp) and hypervirulent (hvKp) strains.

Methods and results

600 clinical specimens were screened for K. pneumoniae. Virulence and resistance fitness were analyzed phenotypically and genotypically. Clinical correlations were assessed to link pathotype, resistance, virulence, infection site, age, and presentation. K. pneumoniae was detected in 17.2% specimens (103/600), with pulmonary samples showing 43% positivity versus 12% in extra-pulmonary ones. hvKp

SUBMITTER: Alshehri F 

PROVIDER: S-EPMC12808397 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature