Real-world Inter-rater Agreement of PI-QUAL Version 2 for Prostate Magnetic Resonance Imaging Quality Assessment and Its Association with Diagnostic Accuracy.

ABSTRACT:

Background and objective

Magnetic resonance imaging (MRI) has been shown to improve the detection of prostate cancer, the second most diagnosed cancer among men. This study evaluates the inter-rater agreement for MRI quality using Prostate Imaging Quality (PI-QUAL) v2. It studies the association of PI-QUAL with diagnostic accuracy and the proportion of indeterminate Prostate Imaging Reporting and Data System (PI-RADS) 3 lesions with PI-QUAL scores.

Methods

This multicenter cohort study included biopsy-naïve patients from the PCAVISION trial (NCT06281769) who underwent MRI for a suspicion of prostate cancer. Four radiologists independently scored PI-QUAL v2 and PI-RADS. PI-QUAL v2 scores were dichotomized as PI-QUAL 1 versus PI-QUAL ≥2. PI-RADS was dichotomized as PI-RADS ≤2

SUBMITTER: van den Kroonenberg DL 

PROVIDER: S-EPMC12809076 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature