Unravelling the Properties of Fluorescent Ammonium Salts to Obtain Thixotropic Hydrogels with Antitumoral Activity.

ABSTRACT: Novel fluorescent and thixotropic hydrogels, based on naphthalimide salts differing for both the cation and anion structure, were obtained and applied as promising bioimaging and antitumoral agents. First, the photophysical behavior of the salts was analyzed through UV-vis and fluorescence investigation at variable solvent and concentration, together with the determination of the relative fluorescence quantum yield in water. Organic salts were also tested as gelators, and the resulting soft materials, obtained in H₂O, H₂O/DMSO mixtures, and glycerol, were characterized by rheological measurements and fluorescence and resonance light scattering analyses. Morphology of gel phases was examined via scanning electron microscopy. To assess their therapeutic potential, the s

SUBMITTER: Billeci F 

PROVIDER: S-EPMC12809299 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature