Selective Copper(II) Complexes against <i>Mycobacterium tuberculosis</i>.

ABSTRACT: The present paper describes the synthesis, characterization, and biological activity of five quinoline derivatives, DCQ; ACQ12; ACQ13; ACQ14; ACQophen, and their respective copper-(II) complexes. The class of organic compounds is composed of 4,7-dichloroquinoline (DCQ) and its derivatives containing aliphatic diamines, 1,2-ethanediamine (ACQ12); 1,3-propanediamine (ACQ13); 1,4-butanediamine (ACQ14); and an aromatic diamine, o-phenylenediamine (ACQophen), as a side chain at the 4-position of the quinoline ring. Single-crystal X-ray diffraction was used to determine the structure of the Cu-DCQ complex (1:2 M:L ratio), while the structure of the Cu-ACQ12 complex (1:1 M:L ratio) was obtained from powder X-ray diffraction (PXRD) data. Spectroscopic (IR, Raman, UV-vis) and analytical data

SUBMITTER: D'Oliveira KA 

PROVIDER: S-EPMC12809329 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature