European Code Against Cancer, 5th edition - hormone replacement therapy, other common medical therapies and cancer.

ABSTRACT: Several medical therapies modify the risk of developing certain cancers in an individual. The aim of this paper was to provide the scientific justification for the 5th edition of the European Code Against Cancer (ECAC5) recommendation on the use of hormone replacement therapy (HRT) and other drugs used at population scale, such as hormonal contraceptives and aspirin. HRT modifies the risk of developing certain cancers in an individual. Except for vaginal oestrogens, all forms of HRT are associated with an increased breast cancer risk; the risk of serous ovarian cancer and endometrial cancer may also be increased. Despite such an increase in cancer risk, HRT often remains the only option for the management of certain menopausal symptoms for the restoration of quality of life and mental heal

SUBMITTER: Thorat MA 

PROVIDER: S-EPMC12809475 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature