Real-Time Identification and Quantification of Per- and Polyfluoroalkyl Substances Using High-Resolution Time-of-Flight Chemical Ionization Mass Spectrometry with Positive Reagent Ions.

ABSTRACT: Per- and polyfluoroalkyl substances (PFAS) are emerging pollutants of concern, primarily due to their terminal degradation products, which exhibit environmental persistence and mobility. Several groups of PFAS, including hydrofluoroolefins (HFOs), perfluoro olefins (PFOs), perfluoro vinyl ethers (PVEs), and hydrofluoroalkanes (HF-alkanes), are volatile and reside predominantly in the gas phase. PFAS such as HFOs, PFOs, and PVEs are considered reactive and may generate short-chain degradation products that persist in the environment. Despite the importance of these gaseous PFAS, there is a lack of analytical techniques capable of providing high-resolution temporal measurements of potential precursors to terminal degradation products. This study presents the first real-time method for detect

SUBMITTER: Gagan S 

PROVIDER: S-EPMC12809635 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature