Systemic inflammation and ex vivo inflammatory responses in first semester university students.

ABSTRACT:

Background

Inflammation contributes to cardiovascular and metabolic disease development. Reducing disease risk by targeting inflammation is therefore desirable in prevention research. However, circulating markers of inflammation are often difficult to detect in younger individuals. Ex vivo stimulated cytokine production offers a promising alternative measure of immune function. Yet, few studies among younger adults have used this measure to date or have assessed its reliability over time.

Methods

First-year university students (N = 110, age 18-19 years) completed two study visits, one each at the beginning and end of their first semester. Circulating cytokines and lipopolysaccharide-stimulated cytokine production were assayed at each visit; composites for each were created u

SUBMITTER: Davis KM 

PROVIDER: S-EPMC12809777 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature