Relapse Following Electroconvulsive Therapy for Schizophrenia: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Evidence regarding schizophrenia relapse following acute electroconvulsive therapy (ECT) is sparse compared with that for depression, and we have no clear consensus on relapse proportions. We aimed to provide longitudinal information on schizophrenia relapse following acute ECT.

Study design

This systematic review and meta-analysis included randomised controlled trials (RCTs) and observational studies on post-acute ECT relapse and rehospitalization for schizophrenia and related disorders. For the primary outcome, we calculated the post-acute ECT pooled relapse estimates at each timepoint (3, 6, 12, and 24 months post-acute ECT) using a random effects model. For subgroup analyses, we investigated post-acute ECT relapse proportions by the type of maintenance therapy

SUBMITTER: Aoki N 

PROVIDER: S-EPMC12809790 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature