Comparative Analysis of Social Cognitive and Neurocognitive Performance Across Autism and Schizophrenia Spectrum Disorders.

ABSTRACT:

Background and hypothesis

Social cognitive and neurocognitive performance is impacted in autism and schizophrenia spectrum disorders (SSDs). Here, we compared social cognitive and neurocognitive performance across a large transdiagnostic sample of participants with autism, SSDs, and typically developing controls (TDCs).

Study design

Participants (total N = 584; autism N = 100, SSDs N = 275, TDCs N = 209; aged 16-55 years; 61% male assigned at birth) completed lower-level (eg, emotion processing) and higher-level (eg, theory of mind) social cognitive tasks, the MATRICS Consensus Cognitive Battery, and a measure of social functioning. Nonparametric groupwise comparisons were undertaken, adjusting for age and sex, and within-group correlations were used to examine associations

SUBMITTER: Rashidi AG 

PROVIDER: S-EPMC12809814 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature