Elevated Blood Pressure in Newborns From Hypertensive Disorders of Pregnancy During the Immediate Postnatal Period.

ABSTRACT: Hypertensive disorders of pregnancy (HDP) impact up to 22% of pregnancies. Offspring from HDP, face an increased risk of future cardiovascular disease, with elevated blood pressure reported as early as childhood. Additionally, primary vascular endothelial cells derived from HDP demonstrate dysfunction in vitro. These data suggest that HDP affect fetal development in ways that impair long-term vascular function, supporting the developmental origins of health and disease (DOHaD) theory that health risks begin before birth. However, it remains unclear at what point these physiological changes first emerge and can be detected systemically. To assess whether changes in cardiovascular function can be detected in the immediate post-natal period, we conducted a retrospective analysis of 1655 mater

SUBMITTER: Freel CI 

PROVIDER: S-EPMC12810192 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature