Neuromotor changes in postural control following bed rest.

ABSTRACT: Chronic bed rest (BR) serves as a model for studying the effects of prolonged immobility on physiological and neuromotor functions, particularly postural control. Prolonged BR leads to significant deconditioning of postural balance control, characterized by increased sway path lengths, sway velocity and fall risk, independent of muscle strength. These changes are linked to neural adaptations at spinal and supraspinal levels, including structural and functional brain changes, such as alterations in grey and white matter, increased cerebellar activation, reduced spinal excitability and increased latencies within reflex circuitries. Additionally, BR disrupts sensory integration from proprioceptive, visual and vestibular systems, impairing postural stability. Visual reliance remains stable dur

SUBMITTER: Ritzmann R 

PROVIDER: S-EPMC12810218 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature