2-(4-Hy-droxy-phen-yl)acetamide.

ABSTRACT: In the title mol-ecule, C₈H₉NO₂, which is an isomer of acetamino-phen [N-(4-hy-droxy-phen-yl)acetamide], the acetamide group plane subtends a dihedral angle of 89.95 (5)° with respect to the phenyl ring plane with the -NH₂ group directed outward, in contrast to an in vacuo DFT geometry optimization in which the -NH₂ group is directed inward. In the extended structure, N-H⋯O hydrogen bonds organize mol-ecules into stacks propagating along [100], with additional hydrogen bonding linking neighboring parallel stacks. A survey of known structures indicates that the structures of 2-phenyl-acetamide mol-ecules with any substitution at the 4-position on the phenyl ring can demonstrate different orientations for the acetamide grou

SUBMITTER: Kester A 

PROVIDER: S-EPMC12810314 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature