Gender-dependent association between cardiovascular health and cognitive function in chinese older adults: a community based cohort study.

ABSTRACT:

Objective

This study investigated the gender-dependent association of cardiovascular health, assessed by Life's Essential 8 (LE8), with cognitive function in Chinese older adults.

Methods

Logistic regression was used to explore the relationships between LE8 scores and incident cognitive impairment as well as cognitive decline. Gender differences were examined by subgroup analyses. A generalized linear model (GLM) was used to assess the mean difference of Mini-Mental State Examination (MMSE) scores across LE8 groups.

Results

Based on logistic regression, LE8 scores were inversely correlated with prevalence of baseline cognitive impairment (OR = 0.49, 95%CI: 0.30,0.84). Higher LE8 scores were associated with reduced risk of incident cognitive impairment am

SUBMITTER: Wang B 

PROVIDER: S-EPMC12810327 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature