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Preparation of Microcapsules Using a Poly(2-(dimethylamino)ethyl methacrylate)-<i>b</i>-poly(benzyl methacrylate) Diblock Copolymer Emulsifier.


ABSTRACT: Most encapsulation techniques require suitable polymers or surfactants to stabilize the microcapsule suspension. Typically, such stabilizers are present in excess in the aqueous continuous phase. In this study, the use of a poly(2-(dimethylamino)ethyl methacrylate)-poly(benzyl methacrylate) (PDMA-PBzMA) diblock copolymer is examined as an efficient stabilizer for the preparation of three types of methacrylic microcapsules with different morphologies. Unlike conventional water-soluble stabilizers, this amphiphilic copolymer is dissolved directly in the dispersed organic phase. This approach minimizes the amount of stabilizer present in the aqueous continuous phase and hence maximizes the formulation efficiency. This new PDMA-PBzMA stabilizer enables either poly(benzyl methacrylate) (PBzMA)

SUBMITTER: Kalleback V 

PROVIDER: S-EPMC12810376 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature