Acute phenylcapsaicin supplementation improves CrossFit® performance: a randomized, triple-blind, placebo-controlled crossover trial.

ABSTRACT:

Background

Phenylcapsaicin (PC) may enhance high-intensity exercise performance by reducing perceived exertion, increasing mechanical output, and limiting muscle damage, making it potentially beneficial for CrossFit^® (CF) athletes.

Objective

To examine the acute effects of PC supplementation on performance, recovery, and metabolic responses during a CF session.

Methods

This study had a randomized, triple-blind, placebo-controlled crossover design. Fifty CF-trained athletes (50% women) ingested either 2.5 mg of PC or a placebo (PLA) 45 minutes before a standardized CF session, including a warm-up, weightlifting block, and WOD. Delayed-onset muscle soreness (DOMS) was assessed 24- and 48-hours post-session. Countermovement jump (CMJ) was evaluated pre- and po

SUBMITTER: Trivino AR 

PROVIDER: S-EPMC12810409 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature