Spontaneous cardiac rupture as the initial presentation of acute myeloid leukaemia complicated by malignant lactic acidosis: a case report.

ABSTRACT:

Background

Left ventricular free wall rupture (LVFWR) without coronary artery occlusion in the setting of acute myeloid leukaemia (AML) is exceedingly rare. We report a rare case of spontaneous cardiac rupture in a patient ultimately diagnosed with acute myeloid leukaemia.

Case summary

A 77-year-old woman presented with acute chest pain and haemodynamic collapse. Coronary angiography revealed no significant stenosis, whereas left ventriculography demonstrated contrast extravasation from the apical region, consistent with LVFWR. The patient underwent emergent surgery; however, no discrete rupture site was identified. Following temporary weaning from cardiopulmonary bypass and re-inspection, no obvious rupture site was observed. Since it appeared that the blow-out-type rupture

SUBMITTER: Umeda Y 

PROVIDER: S-EPMC12810419 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature