Persistent nasal colonization of rare community-acquired methicillin-resistant <i>Staphylococcus aureus</i> clones ST8-IVl (CA-MRSA/J) and ST1930-IVa in healthy adults.

ABSTRACT: As the increase in infections due to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), monitoring of colonization in healthy population is becoming more significant. From nasal cavity of two preclinical medical students who were originally healthy and had neither foreign travel history nor contact with animals, methicillin-resistant S. aureus (MRSA) strains were isolated. For these MRSA, the genotypes, prevalence of virulence factors and antimicrobial resistance determinants were analyzed, along with antimicrobial susceptibility test. These strains were genotyped as (i) ST8-SCCmec-IVl, which was "CA-MRSA/J" clone, known as a unique Panton-Valentine leukocidin (PVL)-negative ST8 MRSA in Japan, and (ii) ST1930-SCCmec-IVa, which belonged to

SUBMITTER: Aung MS 

PROVIDER: S-EPMC12810568 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature