Optimal ratio or historical convention: the use of methanol-ethanol mixtures as pressure-transmitting mediums.

ABSTRACT: We employ a combined computational and experimental approach to systematically assess the hydrostatic properties of methanol-ethanol (MeOH-EtOH) mixtures of varying compositions, with the aim of evaluating their suitability as pressure-transmitting mediums (PTMs). PTMs are essential for enabling the characterization of materials properties at high pressure, perhaps most prominently in the context of diffraction measurements, to provide uniform compression and avoid strain on the sample. Molecular dynamics (MD) simulations indicate that the hydrostatic limit and several structural and dynamic properties of the widely used 4:1 MeOH-EtOH volume ratio do not exhibit any significant deviations from the monotonic trends observed as a function of MeOH content within the mixture. These findings ar

SUBMITTER: Wilson CJG 

PROVIDER: S-EPMC12810705 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature