Prognostic and etiological implications of the susceptibility vessel sign in acute ischemic stroke: An updated meta-analysis.

ABSTRACT: BackgroundThe susceptibility vessel sign (SVS) on MRI has been linked to functional outcomes and reperfusion success after endovascular treatment (EVT), suggesting its potential as a prognostic marker. This updated systematic review and meta-analysis aimed to evaluate the prognostic and etiological significance of SVS in acute ischemic stroke (AIS).MethodsWe conducted a systematic search of PubMed, Embase, and Cochrane in May 2025. Eligible studies included post-hoc analyses of randomized controlled trials (RCTs) and observational studies of AIS patients treated with EVT and/or intravenous thrombolysis (IVT). Pooled risk ratios (RRs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Primary outcome was successful reperfusion (mTICI 2b-3). Secondary outcomes

SUBMITTER: Correia Maciel R 

PROVIDER: S-EPMC12811097 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature