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Preterm infants on high-frequency oscillatory ventilation: electrical impedance tomography during lung recruitment.


ABSTRACT:

Background

We introduce a novel physiological parameter derived from electrical impedance tomography (EIT) to evaluate oxygenation-guided lung recruitment maneuvers in preterm infants on high-frequency oscillatory ventilation (HFOV).

Methods

In this prospective observational study, EIT was performed during a single, stepwise oxygenation-guided lung recruitment maneuver in extremely preterm infants. At each step of continuous distending pressure (CDP), we calculated the median oscillations in the aerated region (MOR), defined as the median of oscillatory impedance amplitudes within the air-containing region multiplied by the number of pixels in that region. Recruitability was determined by a ≥15% increase in MOR or oxygenation (S/F-ratio) during deflation compared to inflatio

SUBMITTER: Werther T 

PROVIDER: S-EPMC12811120 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature