Nutrition interventions in the first 1000 days and long-term health outcomes: a systematic review.

ABSTRACT:

Background

Nutrition in early life can influence health in later life. This systematic review evaluated the impact of nutrition intervention programs in the first 1000 days of life on long-term cardio-metabolic, respiratory, and mental health and dietary behaviour in children.

Methods

Randomized controlled trials (RCTs) from high-income countries were searched in four databases and two trial registries in March 2020, and updated in November 2022. Risk of bias was evaluated using the Cochrane Risk of Bias tool and certainty of results using the GRADE considerations. Results were synthesized narratively.

Results

Sixty-three articles covering 20 interventions were included. Most interventions began in early infancy (<6 months of age), lasted 12-36 months and had follow-u

SUBMITTER: Xu A 

PROVIDER: S-EPMC12811146 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature