Caloric density alters meiotic recombination rate in Drosophila melanogaster.

ABSTRACT: Plasticity in meiotic recombination is a well-documented phenomenon with an unknown mechanism. Recent studies have shown variation in the magnitude and direction of plasticity with a putative connection to organismal stress. Though there have been many factors shown to contribute to recombination rate plasticity, dietary manipulations are understudied. Here we manipulated caloric density, which is known to contribute to well-known life-history trade-offs, to determine if it altered meiotic recombination rates. To investigate the role of genetic background, we selected two stocks from the Drosophila Genetic Reference Panel (DGRP) with varying susceptibility to starvation stress. We found that overall recombination rates increased as calories decreased consistent with previous dietary plasti

SUBMITTER: Novak TE 

PROVIDER: S-EPMC12811279 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature