A Core Effector MoPce1 Is Required for the Pathogenicity of Magnaporthe oryzae by Modulating Catalase-Mediated H₂O₂ Homeostasis in Rice.

ABSTRACT: Plant pathogens employ a diverse array of effectors to facilitate host colonisation, including evolutionarily conserved core effectors. In this study, we identified MoPce1, a CAP/PR-1 domain-containing protein widely distributed among fungal species, as a key virulence factor in Magnaporthe oryzae. Among 72 putative core effectors (PCEs), MoPce1 was found to be essential for pathogenicity but dispensable for asexual development. It localises to biotrophic interfacial complex (BIC) in invasive hyphae (IHs) and to the cytoplasm in Nicotiana benthamiana leaves and rice protoplasts. Ectopic expression of a signal peptide-deleted variant of MoPCE1 (MoPCE1^Δsp) in rice compromised blast resistance and suppressed the reactive oxygen species (ROS) burst. Notably, MoPce1 lacks the conserv

SUBMITTER: Huang J 

PROVIDER: S-EPMC12811410 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature