Incidence and Predictors of Mortality From Low Birth Weight Among Neonates Admitted to Neonatal Intensive Care Units in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Low birth weight (<2500 g) is a major contributor to neonatal mortality in sub-Saharan Africa, yet evidence specific to low birth weight neonates admitted to NICUs remains limited.

Objective

To determine the pooled incidence and predictors of mortality among low birth weight neonates admitted to NICUs in sub-Saharan Africa.

Methods

Following PRISMA guidelines, we searched major databases (2010-2024). Observational studies and randomized trials reporting mortality in NICU-admitted low birth weight neonates were included. A random-effects meta-analysis was conducted.

Results

The pooled mortality incidence was 28.6% (95% CI: 27.70-29.52). Major predictors of mortality were neonatal sepsis (OR 4.15, 95% CI: 3.22-5.36), very low birth weight <1500 g (OR 3

SUBMITTER: Burayu ET 

PROVIDER: S-EPMC12811599 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature