Effectiveness of Closed Blood-Sampling Devices in Critically Ill Adults: A Feasibility Trial.

ABSTRACT:

Background

Anaemia in critically ill patients is often worsened by diagnostic blood sampling. Closed blood sampling devices (CBSDs) may reduce iatrogenic blood loss and transfusion needs. However, robust evidence of their effectiveness and feasibility in the intensive care unit (ICU) setting is lacking.

Aim

To assess the feasibility of conducting a multicentre randomised controlled trial (RCT) evaluating the effectiveness of CBSDs in reducing transfusion requirements in critically ill adults.

Study design

A two-centre, open-label, feasibility RCT was conducted in two Spanish university hospitals between November 2024 and March 2025. Patients with an ICU stay of 24 h who were expected to have an arterial catheter for at least 72 h longer were randomised to either a CBS

SUBMITTER: Raurell-Torreda M 

PROVIDER: S-EPMC12811701 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature