Associations between traumatic brain injury and the prevalence of Alzheimer's disease dementia and behavioral and psychological symptoms of dementia: A retrospective cohort study.

ABSTRACT:

Background

Traumatic brain injury is an environmental risk factor that may accelerate the progression of Alzheimer's disease and behavioral and psychological symptoms of dementia in patients with mild cognitive impairment.

Objectives

To investigate whether traumatic brain injury in patients with mild cognitive impairment is associated with an increased risk of progression to Alzheimer's disease dementia and behavioral and psychological symptoms of dementia.

Design

A retrospective cohort study using the Korean National Health Insurance Service database.

Setting

National-level health data covering healthcare utilization, diagnoses, prescriptions, and procedures in South Korea from January 2012 to December 2021.

Participants

Patients diagnosed with mild cog

SUBMITTER: Kim HK 

PROVIDER: S-EPMC12811773 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature