Emergence of Two New Lineages of the Cosmopolitan Dengue Virus Serotype 2 in Yunnan, China, 2024.

ABSTRACT:

Background

Dengue fever has become a significant epidemic in South and Southeast Asia. Recently, Yunnan Province in southwestern China, which borders these regions, has also experienced a significant outbreak. This study aims to investigate the genetic diversity of the dengue virus (DENV) and identify potential sources of transmission in Xishuangbanna, Yunnan Province in 2024.

Methods

In 2024, we investigated 321 suspected cases of dengue fever in Yunnan Province. We screened dengue fever patients using a combination of DENV NS1 antigen and Pan-qPCR methods, and performed serotype typing using specific qPCR. We also performed phylogenetic and molecular clock analyses to understand the genotypes and transmission sources.

Results

DENV infection was detected in 101 of 32

SUBMITTER: Li M 

PROVIDER: S-EPMC12811849 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature