The Role of Enoxaparin in Influenza Virus Infections and its Therapeutic Implications.

ABSTRACT: Frequent emergence of respiratory viruses with pandemic potential, like severe acute respiratory syndrome coronavirus 2 or influenza, underscores the need for broad-spectrum prophylaxis. Existing vaccines show reduced efficacy against newly emerged variants, and the ongoing risk of new outbreaks highlights the importance of alternative strategies to prevent infection and viral transmission. As respiratory viruses primarily enter through the nose, formulations targeting the nasal epithelium are attractive candidates to neutralize pathogens and thus prevent or minimize infection. Enoxaparin, a low-molecular-weight heparin (LMWH) widely used as an anticoagulant, also exhibits antiviral and anti-inflammatory properties. We found that in highly differentiated human nasal and upper respiratory t

SUBMITTER: Bermejo-Jambrina M 

PROVIDER: S-EPMC12811870 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature