Insights Into Global Antimicrobial Resistance Dynamics Through the Sequencing of Enteric Bacteria From US International Travelers.

ABSTRACT:

Background

Antimicrobial resistance (AMR) is an urgent threat to public health, but gaps in surveillance limit the detection of emergent novel threats and knowledge about the global distribution of AMR genes. International travelers frequently acquire AMR organisms (AMROs) and thus may provide a window into AMR dynamics in otherwise poorly monitored regions and environments.

Methods

To assess the utility of travelers as global AMR sentinels, we collected pre- and post-travel stool samples from 608 travelers between 2017 and 2019, which were screened for the presence of extended-spectrum beta-lactamase producing Enterobacterales, carbapenem-resistant Enterobacterales, and mcr-mediated colistin-resistant Enterobacterales. A total of 307 distinct AMROs were sequenced and analyz

SUBMITTER: Sridhar S 

PROVIDER: S-EPMC12811885 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature