Biomechanical Evaluation of Collagen Membrane Fixation Techniques in Autologous Chondrocyte Implantation: A Comparative <i>In Vitro</i> Study.

ABSTRACT: BackgroundMatrix-induced autologous chondrocyte implantation (MACI) relies on secure collagen membrane fixation for successful cartilage repair. However, comparative biomechanical data on fixation techniques remain limited.ObjectiveTo evaluate and compare the fixation strength of various collagen membrane fixation techniques used in autologous chondrocyte implantation (ACI) using an in vitro porcine model.DesignFifty porcine knees were used to test 17 different fixation methods for securing collagen membranes (Chondro-Gide®). Fixation techniques included various combinations of absorbable and non-absorbable anchors, different suture materials, knotted and knotless techniques, and absorbable pins. Membrane thickness was measured using digital micrometry. Tensile testing was performed

SUBMITTER: Harada H 

PROVIDER: S-EPMC12812514 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature