Cost-effectiveness analysis of tuberculosis screening in diabetic patients in China: a decision-analytic Markov model.

ABSTRACT:

Objective

To establish a pharmacoeconomic model to evaluate the cost-effectiveness of various screening strategies for latent tuberculosis infection (LTBI) in older diabetic patients and provide evidence for health policy formulation.

Methods

A decision tree-Markov model was constructed to simulate the LTBI screening process for 10,000 diabetic patients aged 60 years and older, analyzing the costs and health utilities of different screening strategies.

Results

The incremental cost-effectiveness ratio (ICER) of the traditional tuberculin skin test (TST) strategy was significantly lower than the willingness-to-pay threshold, indicating its economic advantage. Meanwhile, the economic benefit of the new recombinant tuberculosis fusion protein skin test (C-TST) compared to

SUBMITTER: Song HW 

PROVIDER: S-EPMC12813112 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature