Transitions in Psychological Distress Phenotypes and Patient-Reported Outcomes Among Patients Undergoing Total Joint Arthroplasty.

ABSTRACT: Psychological distress is common in individuals undergoing total joint arthroplasty (TJA). Understanding psychological phenotypes and their transitions from before to after surgery can inform risk stratification and targeted care. This study aimed to characterize psychological phenotypes, examine transitions, and compare patient outcomes across phenotypes. This retrospective study included 494 patients who underwent primary hip (43%) or knee (57%) arthroplasty at Duke University Health System (2018-2024). Latent transition analysis identified and examined transitions of psychological phenotypes preoperatively and postoperatively using the Optimal Screening for Prediction of Referral and Outcome Yellow Flag tool. Demographic characteristics, phenotype transitions, Patient-Reported Outcomes

SUBMITTER: Ramirez MM 

PROVIDER: S-EPMC12813621 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature