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A Concise Total Synthesis of (+)-Pedrolide.


ABSTRACT: A concise total synthesis of (+)-pedrolide has been accomplished. Key steps include an intramolecular Diels-Alder reaction to rapidly construct the tetracyclic carbon skeleton from (R)-carvone and the late-stage application of two different MHAT reactions in advancing the highly functionalized carane moiety.

SUBMITTER: Shen H 

PROVIDER: S-EPMC12814354 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature