Dataset Information

Cardiovascular magnetic resonance feature tracking for rejection surveillance after cardiac transplantation.

ABSTRACT:

Background

Endomyocardial biopsy (EMB) is the standard invasive method for monitoring acute cardiac allograft rejection (ACAR); however, non-invasive alternatives are increasingly proving to be dependable.

Objectives

We aimed to identify and validate dependable cardiovascular magnetic resonance (CMR) strain indices for ACAR detection.

Methods

We analyzed 160 CMR scans, including long- and short-axis cines, as well as T1/T2 maps from 54 transplant recipients. Uniparametric and multiparametric models integrating left ventricular strain metrics and tissue characteristics were developed to classify histological rejection grades (0, 1 R, ≥2 R) and evaluate therapeutic response.