Severe maternal morbidity and risk of transplant rejection in pregnant patients with a history of solid-organ transplant.

ABSTRACT:

Background

In 2023, 18,078 US women underwent solid organ transplants; over a third (n = 5547) were of reproductive age, receiving kidney (69.6%), liver (23.7%), or heart (9.0%) transplants. Successful pregnancies are feasible for transplant recipients, but these patients often face elevated pregnancy risks, including hypertension, gestational diabetes, pre-eclampsia, and preterm birth.

Objective

To determine rates of severe maternal morbidity (SMM) associated with prior kidney, liver, or heart transplant.

Study design

This descriptive study was conducted using the TriNetX Research Network, a health research network with data from 95 health care organizations spanning 1/1/2010-10/29/2024. Patients aged 12-55 years were included if they underwent single solid organ tra

SUBMITTER: Jarvis A 

PROVIDER: S-EPMC12814856 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature