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ABSTRACT: Purpose
To quantify the value of using prior changes in spherical equivalent refractive error (SER) and axial length (AL) to predict future myopia progression.Methods
For this post hoc analysis of a randomized controlled trial, we used data from children ages 5 to 12 years with SER -1.00 to -6.00 D who had been randomized 2:1 to 0.01% atropine or placebo eye drops for 24 months. Multivariable linear regression evaluated the association of baseline-to-12-month change in SER and AL versus 12-to-24-month change while controlling for age and SER or AL at 12 months. Treatment groups were pooled for analyses; sensitivity analyses were conducted using only the placebo group.Results
Among 187 children, 136 (73%) with complete data were included. For predicting a 0.50-D-or-m
SUBMITTER: Beaulieu WT
PROVIDER: S-EPMC12814979 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature