Socio-Economic Determinants and Regional Prevalence of Disorders of Gut-Brain Interaction in the Netherlands: Results From the Rome Foundation Global Epidemiology Study.

ABSTRACT:

Background

Disorders of gut-brain interaction (DGBI) impose significant burdens worldwide, yet reliable regional prevalence estimates are lacking, limiting insight into potential geographic variation. Socio-economic status (SES) may contribute but remains underexplored.

Methods

Data were obtained from the Dutch cohort of the Rome Foundation Global Epidemiology Study, including the Rome IV Adult Diagnostic Questionnaire, sociodemographic items, and SES indicators. The Netherlands was divided into three regions (Region 1: South; Region 2: West; Region 3: North-East). Regional prevalence was calculated for any DGBI, groups, and subtypes. Associations with SES were examined using logistic regression.

Key results

2008 participants (50% female; age: 48 years [IQR: 31]; BMI:

SUBMITTER: Veldman F 

PROVIDER: S-EPMC12814999 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature