Novel thiosemicarbazone UV-vis chemosensor for dual pH-orthogonal detection of Fe³⁺ and Ag^.

ABSTRACT: The selective and sensitive detection of transition and coinage metal ions remains a formidable challenge in environmental and biomedical analysis. We introduce 2-(2-(allyloxy)benzoyl)-N-ethylhydrazine-1-carbothioamide (S3), a novel thiosemicarbazone-based soft-donor ligand, as a dual-mode UV-Vis chemosensor that discriminates between Fe³⁺ and Ag⁺ under pH control. The chemical structure of the newly synthesized ligand S3 was confirmed by elemental analysis, FT-IR, UV-Vis, and NMR spectroscopy. Upon titration with Fe³⁺ in NH₄Cl/NH₃ buffer (pH 10), a broad ligand-to-metal charge-transfer envelope develops across 450-650 nm with a bathochromic shift of λ _max from ∼540 to ∼620 nm. Hill analysis (n = 1.16, <

SUBMITTER: Ali SAM 

PROVIDER: S-EPMC12815369 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature