Cognitive changes in post-stroke depression patients undergoing treatment with transcranial direct current stimulation (tDCS): an exploratory, ancillary analysis of a randomized, sham-controlled clinical trial.

ABSTRACT:

Objective

Post-stroke depression affects approximately 40% of stroke survivors, with cognitive deficits being frequently observed. Transcranial direct current stimulation (tDCS) has shown promise in improving cognitive performance in stroke patients. We explored the effects of tDCS on cognitive performance in post-stroke depression.

Methods

We conducted an exploratory analysis of 48 patients from a double-blinded, shamcontrolled, randomized clinical trial that investigated the effects of tDCS on post-stroke depression. A neuropsychological battery was applied at baseline and endpoint. We assessed three key domains: 1) the Stroop effect, measured with Stroop Test components (the color-naming, word-reading, and word-color interference tasks); 2) processing speed, measured with

SUBMITTER: Zanao T 

PROVIDER: S-EPMC12815390 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature