Dynamic cerebral autoregulation in infants undergoing major non-cardiac surgery.

ABSTRACT: Dynamic cerebral autoregulation (CAR) is the capacity in the cerebral vessels to attenuate the effect of rapid changes in blood pressure (BP). NeoDoppler, a novel ultrasound system, monitors cerebral blood flow velocity (CBFV) through an open fontanel continuously. Our primary aim was to evaluate dynamic CAR using continuous Doppler in infants undergoing major non-cardiac surgery. The pressure-flow relationship was evaluated in the time- and frequency domain, and the two methods were compared. The secondary aim was to compare this with near-infrared spectroscopy (NIRS). CBFV and regional oxygenation were synchronized with invasive BP monitoring. Nineteen infants (ten preterm) were included. In the time-domain, NeoDoppler showed that the mean proportion of time with impaired CAR was highest

SUBMITTER: Vik SD 

PROVIDER: S-EPMC12815638 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature