Ultrabrief pulse electroconvulsive therapy for depression: a systematic review and meta-analysis.

ABSTRACT: Ultrabrief pulse (<0.5 millisecond pulse width) electroconvulsive therapy (ECT) is regarded as a cognition-sparing form of ECT. Contrary to some early research, recent randomised trials have reported low remission rates with ultrabrief pulse high-dose right unilateral ECT. The aim of the present systematic review and meta-analysis was to assess acute and long-term outcomes following right unilateral and bilateral forms of ultrabrief pulse ECT in depression. We searched PubMed, Embase, PsycINFO, CENTRAL and ClinicalTrials.gov databases from 01 January 2007 to 17 September 2024 for randomised controlled trials and observational studies reporting on one or more relevant outcomes. Remission, response, relapse and switching rates to other forms of ECT were pooled using random effects models. 30

SUBMITTER: Jelovac A 

PROVIDER: S-EPMC12815675 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature