Brain functional changes following spinal manipulation therapy in patients with lumbar disc herniation and chronic low back pain: a scoping review.

ABSTRACT:

Purpose

Chronic low back pain (LBP) is a common symptom in patients with lumbar disc herniation (LDH), and spinal manipulation-related therapies can alleviate pain. This study aimed to review the clinical research evidence regarding the central nervous mechanisms of spinal manipulation in treating chronic lower back pain related to lumbar disc herniation, summarize the current state of research, identify existing gaps, and lay the foundation for future studies.

Methods

This scoping review was conducted according to established methodological frameworks. Original studies were retrieved from eight databases from inception to August 1, 2025. Of the 169 articles, 10 were ultimately selected as meeting the inclusion criteria. The data were systematically organized and categorized

SUBMITTER: Cao L 

PROVIDER: S-EPMC12815715 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature