Shifting burden of nasopharyngeal carcinoma: global patterns and forecasts to 2050 from the GBD 2021.

ABSTRACT:

Background

Nasopharyngeal carcinoma (NPC) exhibits pronounced geographical variation, with a high burden in specific regions. We assessed global, regional, and national trends in NPC burden from 1990 to 2021 and projected estimates to 2050.

Methods

We analyzed data from the Global Burden of Disease (GBD) 2021 study for 204 countries and territories across 21 regions. Age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), and age-standardized disability-adjusted life-years (DALYs) rate were estimated, and temporal trends were assessed using estimated annual percentage change (EAPC) by socio-demographic index (SDI), sex, and age group. Future burden from 2022 to 2050 was projected using a Bayesian age-period-cohort model.

Results

In 2021, there were

SUBMITTER: Zhou E 

PROVIDER: S-EPMC12815733 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature