The effect of intraoperative hypotension on postoperative delirium: a meta-analysis and systematic review.

ABSTRACT:

Background

Postoperative delirium (POD) is a common complication linked to poor outcomes, yet its relationship with intraoperative hypotension (IOH) remains unclear. The objective of this study was to clarify the association between intraoperative IOH and POD.

Method

We searched four databases (PubMed, EMBASE, Cochrane Library, and Web of Science) from their inception to June 14, 2025. Randomized controlled trials (RCTs) and observational studies were included when IOH was incorporated as a predictive variable for POD in adult patients undergoing elective surgery under general anesthesia. Risk ratio (RR) and odds ratio (OR) were calculated using a random-effect model separately in RCTs and observational studies.

Results

In total, thirty out of 1,261 studies were inclu

SUBMITTER: Yin X 

PROVIDER: S-EPMC12816188 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature