Oral microbiota in an aging Swedish population with high dental disease burden: an observational registry-based study.

ABSTRACT:

Introduction

The global population is aging. Although aging populations experience a high burden of dental and systemic diseases, few studies have described the oral microbiota in aging population-based cohorts. This observational, registry-based study aimed to characterize the diversity and composition of the oral microbiota in 1,093 aging Swedes-aged 54-84 years at inclusion-and evaluate associations with host traits, as well as prospective measures of caries and periodontal status.

Methods

Saliva microbiota was characterized using complete 16S rRNA gene sequencing, and dental data were obtained from primary care dental records. Partial least squares regression was used to identify species associated with variation in age, number of teeth, total number of sequence reads, c

SUBMITTER: Esberg A 

PROVIDER: S-EPMC12816219 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature