Naturalistic investigation of cannabis strains varying in THC and CBD ratios and verbal recognition memory.

ABSTRACT:

Introduction

Cannabis, which contains cannabinoids delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), has become the third-most-commonly used psychoactive substance in the United States. The legal market has grown alongside the increase in adult cannabis use, resulting in greater availability of products with a wide range of THC and CBD content. One of the most consistently observed cognitive effects of cannabis use is impairment of verbal memory. Although previous research shows that THC reduces accuracy in verbal memory tasks, less is known about potential differential acute effects of THC and CBD on recognition memory. Previous studies have suggested a protective effect of CBD (when combined with THC) on recognition memory, though research is mixed.

Methods

In the

SUBMITTER: Paulich KN 

PROVIDER: S-EPMC12816388 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature